this post was submitted on 24 Jun 2025
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I actually thought about this a few years ago, is it possible that we age because of oxidation to some degree? Is there a way to prevent that? I thought about it, how blood can rust and just had the connecting thought but I'm not smart enough to know if there's any actual correlation.
Pretty sure oxidation plays a major role in aging, but can't tell you the exact mechanism, I have no idea about it.
But about the blood rust idea, I don't think that can work, cause we don't have just iron particles that can directly interact with oxygen just floating around in our blood, we have a complex (I.e. hemoglobin) that contains significant amounts of iron, which somehow makes it really good for binding to and carrying oxygen.
Deviating a bit, carbon monoxide poisoning is really akin to suffcation iirc, cause it binds and occupies the hemoglobin, effectively reducing the amount of oxygen that can be carried by your blood.
However, do fact check me, I might be wrong about something...
Edit: BTW, it seems that "oxidation" might not be the right term to use here, so do understand that I am referring to free radicals here.
You're pretty much right about everything. Oxygen (especially as free radicals) is damaging to pretty much all your tissues, so your body moves it around in little bodyguard proteins (hemoglobin). These each contain 4 small iron molecules as part of the much bigger structure and doesn't rust or function like iron in any way. The iron is mostly used for electrons (and also damages your body if it's not inside the hemoglobin and causes more aging)
Carbon monoxide has a higher affinity for hemoglobin than oxygen, so it sticks to your blood cells and makes them useless for hours. Super dangerous.
Point being "oxidative stress" is bad for you and a major cause of aging that your body tries to fight. If your body doesn't fix this well, you age faster. If it repairs damage too well, you're more prone to cancer. Just wear and tear of using your body.
So to the original question of can this process be stopped... Absolutely! Hold your breath - the oxygen will stop coursing through your body and you will stop aging. Just ten minutes is enough to end aging indefinitely! Then you have to worry about other problems like body decomposition, but the oxidative stress will be cured!
Carbon monoxide, not dioxide.
I'm no expert but I'm fairly sure that is basically true in a way. As per zr0's top-level comment. Forms of life that can make do with less cellular respiration, for example by using external sources to regulate temperature (cold- blooded), don't need to invite as much oxygen into their cells, and so they get less weird damage over time. Mammals in general have not adopted this strategy.