Luigi Mangione

True, but if the prosecution seeks the death penalty (which is likely), any jurors that say they'd have difficulty condemning someone to death will be automatically disqualified with no strikes used.

Since people who don't have any problems with the death penalty is MUCH more likely to have a clear bias in favor of the prosecution and the cops are good at spotting people lying in order to get on (or off) a jury, making it a death penalty case all but eliminates any chance of a fair trial.

But a strike can't bring back in someone who has been eliminated. You can use your strikes to whittle away people who have a property likely to be bad for you, but you can't use it to include people with a quality that would be good for you.