Large amounts of alcohol would be the same thing as it all depends on your mass weight, tolerance, how often you've been drinking (which by the way works both ways ... you could have been drinking regularly for ten years and have a strong tolerance for alcohol, or you could have been drinking regularly for 15 years and now your liver is shot and you have no more tolerance)

The thought of race and cultural background came to me because I was thinking of lactose intolerance which is culturally specific to different groups of people who historically didn't drink milk or milk products. I'm indigenous Canadian and I'm lactose intolerant and I remember being a teen and entering into a challenge with a friend who was white into drinking milk shakes. I knew I was lactose intolerant but I was a dumb kid. I think we both drank four large milkshakes and we didn't win or lose and just laughed at drinking that much milkshake. He didn't think twice about it. I went home, farted continuously for hours and felt like my stomach wanted to explode, it was actually painful. Just at the point where I was scared and wanted to go to the hospital, it got better and I got over it. Ever since then it made me think that if I had just a bit more, it would probably kill me.