The instance seems to be mostly right wing trolls. I know defederating is unpopular but I don't think much is to be lost in this case and it can save the mods some headaches.
Edit: the response on exploding-heads.com to my reporting of transphobia. Courtesy of the "second in command"
There's no way I'm going to read all of that but I scanned it and caught a "I have many gay friends" and said ayup, there it is.
They are also using a hermaphrodite cousin as a token trans friend.