ylai

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[–] ylai@lemmy.ml 27 points 10 months ago* (last edited 10 months ago) (1 children)

He was criticized also because the girls were not in danger of becoming infected. See e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724388/ :

The Chinese episode has also generated other issues. Several notes demonstrate that this was an experiment and not a therapeutic intervention (even He Jiankui called it a 'clinical trial'). The babies were not at risk of being born with HIV, given that sperm washing had been used so that only non-infected genetic material was used. Further, even though one of the parents (or both) was infected, it did not mean the children were more prone to becoming infected. The risk of becoming infected by the parents' virus was very low (Cowgill et al., 2008). In sum, there was no curative purpose, nor even the intention to prevent a pressing risk. Finally, the interventions were different for each twin. In one case, the two copies of CCR5 were modified, whereas in the other only one copy was modified. This meant that one twin could still become infected, although the evolution of the disease would probably be slower. The purpose of the scientific team was apparently to monitor the evolution of both babies and the differences in how they reacted to their different genetic modifications. This note also raised the issue of parents' informed consent regarding human experimentation, which follows a much stricter regimen than consent for therapeutic procedures.

Other critical articles (e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524470/) have also cited in particular https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779710/, which states in the result section:

No HIV transmission occurred in 11,585 cycles of assisted reproduction using washed semen among 3,994 women (95% confidence interval [CI] = 0–0.0001). Among the subset of HIV-infected men without plasma viral suppression at the time of semen washing, no HIV seroconversions occurred among 1,023 women following 2,863 cycles of assisted reproduction using washed semen (95%CI= 0–0.0006). Studies that measured HIV transmission to infants reported no cases of vertical transmission (0/1,026, 95% CI= 0–0.0029). Overall, 56.3% (2,357/4,184, 95%CI=54.8%–57.8%) of couples achieved a clinical pregnancy using washed semen.

[–] ylai@lemmy.ml 5 points 11 months ago (2 children)

GIMP is a special case. GIMP is being getting outdeveloped by Krita these days. E.g.:

https://gitlab.gnome.org/GNOME/gimp/-/issues/9284

Or compare with:

https://www.phoronix.com/news/Krita-2024-GPUs-AI

GIMP had its share of self inflicted wounds starting with a toxic mailing list that drove away people from professional VFX and surrounding FilmGimp/CinePaint. When the GIMP people subsequently took over the GEGL development from Rhythm & Hues, it took literally 15 years until it barely worked.

Now we are past the era of simple GPU processing into diffusion models/“generative AI” and GIMP is barely keeping up with simple GPU processing (like resizing, see above).

[–] ylai@lemmy.ml 6 points 11 months ago* (last edited 11 months ago)

Have people actually checked the versions there before making the suggestion?

F-Droid: Version 3.5.4 (13050408) suggested Added on Feb 23, 2023
Google Play: Updated on Aug 27, 2023

https://f-droid.org/en/packages/org.videolan.vlc/
https://play.google.com/store/apps/details?id=org.videolan.vlc

The problem seems to be squarely with VLC themselves.

[–] ylai@lemmy.ml 3 points 11 months ago

From my own statistics how many I feel worthy posting/linking on Lemmy, the most direct alternative to Kotaku is Eurogamer. PCGamer, PCGamesN and Rock Paper Shotgun are occasionally OK, but you have to cut through a lot of spam and clickbait (i.e. exactly this “50 guides per week” type of corporate guidance). Not sure if this is also the state that Kotaku will end up in. The Verge sometimes also have good articles, but the flood of gadget consumerism articles there is obnoxious.

[–] ylai@lemmy.ml 2 points 11 months ago

It is like the U.S. Wired catching up to the idea years later?

[–] ylai@lemmy.ml 1 points 11 months ago* (last edited 11 months ago)

The PS Vita side of Sony customer has gotten a deep taste of Sony’s issues of catering everything to a singular console. And same with PSVR2: Of course it must be PS5 exclusive, because everything are adornments towards their shiny console — and went on to not sell a lot of PS5.

[–] ylai@lemmy.ml 19 points 11 months ago (1 children)
[–] ylai@lemmy.ml 23 points 11 months ago (3 children)

In the beginning, only privileged ones will be allowed to run in pass-through mode. But goal/roadmap calls for all FUSE filesystems eventually to have this near-native performance.

[–] ylai@lemmy.ml 13 points 11 months ago (4 children)

Well, if you have a constructive suggestion which site to link instead regarding kernel developments, I am all ears:

  • Not sure that raw commits are readable or have sufficient context for non kernel development readers here
  • LWN, particularly timely/kernel development news there, has gone mostly paywall, and there will be (legitimate) complaint if I link articles needing a LWN subscription
[–] ylai@lemmy.ml 21 points 11 months ago (6 children)

Not sure what called for this blatant personal attack. My post history speaks for itself, quite in comparison to yours. And Phoronix is well-known Linux website, and its test suite is in fact even referenced in various regression tests/patches in LKML (also not sure what/if any kind of kernel development you have done).

[–] ylai@lemmy.ml 7 points 11 months ago (1 children)

See https://knowyourmeme.com/memes/u-mad, in particular the “Due to the agitating nature of the phrase, it is often considered a form of trolling.”

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