this post was submitted on 17 Mar 2025
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Science Memes

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submitted 22 hours ago by fossilesque@lemmy.dbzer0.com to c/science_memes@mander.xyz
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[–] andros_rex@lemmy.world 15 points 7 hours ago* (last edited 7 hours ago)

Also - there are known negative interactions of that mutation with other diseases.

From wiki:

CCR5 Δ32 can be beneficial to the host in some infections (e.g., HIV-1, possibly smallpox), but detrimental in others (e.g., tick-borne encephalitis, West Nile virus). Whether CCR5 function is helpful or harmful in the context of a given infection depends on a complex interplay between the immune system and the pathogen.

What he did was flat out unethical and completely unjustifiable. If he had discussed the risks and benefits with the parents, ran it past an IRB, then maybe we could be having a conversation about the ethics of “playing god.”

Edit: also, he fucked up and the girls have mosaicism/no enhanced HIV resistance. Wonder how good a job he did with his CRISPR…