this post was submitted on 13 Aug 2025
48 points (75.5% liked)

Science

5139 readers
38 users here now

General discussions about "science" itself

Be sure to also check out these other Fediverse science communities:

https://lemmy.ml/c/science

https://beehaw.org/c/science

founded 3 years ago
MODERATORS
top 50 comments
sorted by: hot top controversial new old
[–] lIlIlIlIlIlIl@lemmy.world 62 points 5 days ago (12 children)

This is fear mongering disguised as “science”

A population-based retrospective cohort study of 9.8 million people in Ontario, Canada, found that people with an emergency department visit for cannabis use or cannabis-induced psychosis were at a 14.3-fold and 241.6-fold higher risk of developing a schizophrenia-spectrum disorder within 3 years than the general population, respectively.4

So another way to state this: people who are prone to mental health disorder are likely to LEARN ABOUT IT with cannabis, but it’s not causing healthy people to go crazy

Some prohibitionist jumped on this to spin it as propaganda

[–] atomicbocks@sh.itjust.works 11 points 4 days ago (2 children)

It sure sounds like they’re just saying that cannabis helped people detect schizophrenia earlier than they normally would have. Which would strike me as a good thing…

[–] kibiz0r@midwest.social 11 points 4 days ago (2 children)

Yall are sayin stuff like “learn about” and “detect” as if they got to just add that to their notes and continue on their day.

Going from “might develop schizophrenia some day” to “inpatient for an episode right now” is a big difference.

[–] atomicbocks@sh.itjust.works 4 points 4 days ago (2 children)

Schizophrenia is better treated the earlier it is diagnosed. We are not talking about people who “might develop schizophrenia one day” but those who found out they had it as a result of this process perhaps earlier than they would have otherwise.

[–] frongt@lemmy.zip 7 points 4 days ago

I'm not sure that finding out by having an episode triggered that results in hospitalization is a good thing.

[–] medgremlin@midwest.social 1 points 3 days ago

The earlier its diagnosed, the more severe it tends to be. If someone has schizophrenia triggered under the age of 25, the massive shift in the balance of neurotransmitters has a significant effect on the continuing development of the brain. The frontal cortex (the executive function, intelligence/wisdom, and common sense part of the brain) is the last part to finish developing. That's why you can have teenagers and college-aged kids that are extremely smart academically, but absolute morons when it comes to decision making and self-restraint.

Schizophrenia is characterized by massive overloading of dopamine to the point that the brain malfunctions, and the medications used to treat it (anti-psychotics) mostly work by dulling the effects of dopamine and limiting its production. Finding the right anti-psychotic and right dose of that drug can take a lot of trial and error, and that's all time lost for ongoing development of that person's brain. Dopamine is a very important neurotransmitter, so if someone has severe schizophrenia requiring strong dopamine inhibition, they can end up with a lot of nasty side effects.

The medications have long term effects too and there's kind of a maximum amount of time you can be on an anti-psychotic before you start having a form of medication-induced Parkinsonism. If someone's schizophrenia gets triggered then diagnosed and treated earlier, it means they are going to start having those Parkinson's symptoms that much earlier.

[–] ushmel@piefed.world 1 points 3 days ago

Every time you experience psychosis, it increases your chance of experiencing it again, independent of your previous risk. Each episode makes it more likely. Unfortunately drug induced can make it worse.

[–] medgremlin@midwest.social 8 points 4 days ago (2 children)

Schizophrenia is a mental health disorder that can be triggered by psychoactive substances, trauma, or other significant events/life changes. Not everyone who has schizophrenia was guaranteed to get it, it's just that some people have the potential for it. A psychotic episode (whether substance-induced or organic) is a common trigger to cause schizophrenia in someone that had the potential to develop the disorder.

If you have a family history of mental illnesses (particularly Schizophrenia and Bipolar disorder), significant THC use and substance-induced psychotic episodes can be the grain that tips the scale towards developing the disorder that may have otherwise been avoided.

(TL;DR: if Schizophrenia runs in your family, be exceedingly careful about what psychoactive substances you use.)

[–] otter@lemmy.dbzer0.com 3 points 3 days ago (1 children)

Yep. I had a close friend that accepted a grip of shrooms from some random chicks at a house party, only to find out the hard way that night that his estranged (since ~birth) father's side of the family had a high risk for schizophrenia... Be careful, friends. Knowledge is power. Use your damn brains, please.

[–] medgremlin@midwest.social 5 points 3 days ago

I work in medicine (mostly emergency medicine), and I have seen a lot of people end up with their lives completely torn apart because of permanent effects of psychotropic drugs. CBD has a lot of benefits and some real clinical evidence backing it up, but there really aren't any non-recreational uses for THC and the people who want to use marijuana for calming effects can get CBD on its own these days.

[–] bathing_in_bismuth@sh.itjust.works 2 points 3 days ago (1 children)

Someone has to be the first so your descendants can say it runs in the family.

[–] medgremlin@midwest.social 1 points 3 days ago

Given that, as a species, we have only just recently figured out how to diagnose any of these things, it is highly unlikely that these conditions are nowhere in your family lineage. There is always the possibility of de novo mutations that can shake things up, but people with schizophrenia used to just be called generically insane...or they were prophets or cult leaders if they rolled high on Charisma.

[–] medgremlin@midwest.social 8 points 4 days ago

Copied from another reply:

Schizophrenia is a mental health disorder that can be triggered by psychoactive substances, trauma, or other significant events/life changes. Not everyone who has schizophrenia was guaranteed to get it, it’s just that some people have the potential for it. A psychotic episode (whether substance-induced or organic) is a common trigger to cause schizophrenia in someone that had the potential to develop the disorder.

If you have a family history of mental illnesses (particularly Schizophrenia and Bipolar disorder), significant THC use and substance-induced psychotic episodes can be the grain that tips the scale towards developing the disorder that may have otherwise been avoided.

(TL;DR: if Schizophrenia runs in your family, be exceedingly careful about what psychoactive substances you use.)

load more comments (10 replies)
[–] vala@lemmy.dbzer0.com 9 points 4 days ago* (last edited 4 days ago) (3 children)

I get that this is fear mongering propaganda but also, I kinda hate that you can't buy any old school pot anymore.

28% THC with no CBD just isn't very enjoyable to me tbh.

I miss that stuff that was like 18% THC and at least 0.5% CBD.

[–] otter@lemmy.dbzer0.com 4 points 3 days ago* (last edited 3 days ago)

1.) It's stupid easy to grow your own for next to nothing, in "stealth" containers ranging from 5gal buckets to full-on multi-plant gargants. (See: "space buckets" — and check your local laws)

2.) It's called weed for a reason. Set a reminder on your phone to water, prune, tend to your buddy. Spend as little or as much as you feel like, depending on how into the new, meditative hobby you've embarked on.

3.) Realize you've been spending far too much on something you can set & (mostly) forget.

4.) Enjoy!

[–] Honytawk@feddit.nl 5 points 4 days ago

You can also just buy straight up CBD and mix until your hearts content.

You don't have to fill it to the brim with high grade pot if you don't want to.

load more comments (1 replies)
[–] ABetterTomorrow@sh.itjust.works 21 points 5 days ago (1 children)

I was using pretty hard after my mom died. Numbing myself every night for two years, it really messed myself up and my partners life. After taking a break for 4 months I saw and felt what it was doing to me and decided to reduce and use a different form for more control if needed. I take a gummy on fridays and Saturdays now, finally found the best option for me and sticking to it for almost 7 months. Be safe everyone.

[–] some_guy@lemmy.sdf.org 13 points 4 days ago

Too much of any mind-altering substance will cause mental debilitation at some point. Moderation in all things. I say this as someone who has gone hard on a few different drugs (including alcohol) throughout my life.

[–] bathing_in_bismuth@sh.itjust.works 4 points 3 days ago (1 children)

The "but alcohol is worse and its legal" crowd really rustles my jimmies in a bad way. I propose any reader to go trough every comment and post the best arguments for this being "fearmongering propaganda" under this reply.

[–] Killer57@lemmy.ca 1 points 3 days ago* (last edited 3 days ago) (1 children)

Man it almost like there is a known correlation between alcohol and violence or something.

[–] bathing_in_bismuth@sh.itjust.works 1 points 3 days ago (1 children)

Yeah there is sociatal harm and personal harm. Both alcohol and THC can be damaging in their own ways. Your point?

[–] Killer57@lemmy.ca 0 points 3 days ago (1 children)

Show me the studies proving that THC is even remotely close to as bad as alcohol for you, THC sure as shit isn't going to kill your liver either!

[–] bathing_in_bismuth@sh.itjust.works 2 points 3 days ago (1 children)

You'd have differ between public harm and self harm. Also you miss the point, both can be bad in different ways. The links of THC use under 25 leading to psychosis and trigger/cause early onset of schizophrenia are more than established. I won't choose between liver cirrhosis and mental health problems because both ruin your life. You don't need organ failure rot in a clinic or become homeless with schizophrenia and off yourself. I've seen both substances ruin lives and my country of residence has infinitely better, and free, mental health care.

[–] Killer57@lemmy.ca 1 points 2 days ago* (last edited 2 days ago) (1 children)

Please let me be as transparent as possible about this, I am a bud tender working in Canada, I sell legal cannabis to people right beside a liquor store. Cannabis has been legal up here for coming up on 10 years, and yet, I still haven't seen any proof of what you are trying to say. So at the end of the day, please let the people who haven't been allowed to research cannabis usage under prohibition research and report their findings.

[–] bathing_in_bismuth@sh.itjust.works 1 points 2 days ago* (last edited 2 days ago)

I don't think people with schizophrenia will still be visiting your store. I am pro legalisation of cannabis, but the possible consequences should not be dismissed as propaganda.

For example: https://pubmed.ncbi.nlm.nih.gov/30373388/ (https://pmc.ncbi.nlm.nih.gov/articles/PMC6591882/)

Now I agree that you could assert, in the case of depression and anxiety, these results could mean someone is self-medicating for said mental problems, thus clouding the objectivity. But that is not the case with psychosis. Not at all. That is entirely correlated to cannabis (and my personal research concludes this has to do with an increase trend of higher THC contents of strain in the past 30 years. A joint in 1995 is a hell of a lot different experience compared to today's strains [yes I know there are strains focussing on CBD or other cannabinoids like CBG etc. But let's not compare apples and oranges. Take a strain from 1995 and today, picked with the sole reason of getting high, and today's strains will have a lot higher THC contents])

Normally I dislike editorial pieces but this one refers to solid papers: https://www.scientificamerican.com/article/the-link-between-cannabis-and-psychosis-in-teens-is-real/

I don't think anyone in cluster A or B (some specific diagnoses of cluster C maybe) should be near drugs. And especially THC, because of its image (its just weed, it doesn't cause any harm). A lot of people self-medicate. I don't want to create an illusion of there not being any precautions needed. People who use shouldn't Russian roulette and find out if they are on cluster a or b, very likely increase early onset of symptoms or maybe even trigger something as permanent as schizophrenia. Even a single psychosis with no follow up episodes can fuck your life up good.

[–] LodeMike@lemmy.today 12 points 5 days ago

This isn't hidden this is well known stuff

[–] Zamboni_Driver@lemmy.ca 5 points 4 days ago

This article brought to you by Budweiser

[–] LustyArgonianMana@lemmy.world 2 points 4 days ago* (last edited 4 days ago) (1 children)

Willie Nelson looks great and sounds great for his age, with a case study like that I'm not putting down the cannabis

[–] Honytawk@feddit.nl 1 points 4 days ago (1 children)

I mean, outliers always exist. Don't think those are the norm.

[–] LustyArgonianMana@lemmy.world 1 points 3 days ago

By definition of what a norm is, no, an outlier wouldn't be the norm. But who's to say Willie's physical reaction to cannabis is an outlier?

load more comments
view more: next ›